Akt-mediated Ephexin1–Ras interaction promotes oncogenic Ras signaling and colorectal and lung cancer cell proliferation

Ephexin1 was reported to be highly upregulated by oncogenic Ras, but the functional consequences of this remain poorly understood. Here, we show that Ephexin1 is highly expressed in colorectal cancer (CRC) and lung cancer (LC) patient tissues. Knockdown of Ephexin1 markedly inhibited the cell growth...

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Detalles Bibliográficos
Autores principales: Kim, Jeeho, Jeon, Young Jin, Lim, Sung-Chul, Ryu, Joohyun, Lee, Jung-Hee, Chang, In-Youb, You, Ho Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8553951/
https://www.ncbi.nlm.nih.gov/pubmed/34711817
http://dx.doi.org/10.1038/s41419-021-04332-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8553951/
https://www.ncbi.nlm.nih.gov/pubmed/34711817
http://dx.doi.org/10.1038/s41419-021-04332-0

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