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Influence of Cytochrome P450 2C19 Genotype on Helicobacter pylori Proton Pump Inhibitor-Amoxicillin-Clarithromycin Eradication Therapy: A Meta-Analysis

Background: Proton pump inhibitors (PPIs) are the first-line treatment for acid-related diseases. The pharmacokinetics and therapeutic efficacy of PPIs, however, are influenced by genetic factors such as variants in genes encoding drug-metabolizing enzymes (e.g., cytochrome P450 2C19 [CYP2C19]) and...

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Detalles Bibliográficos
Autores principales: Morino, Yuko, Sugimoto, Mitsushige, Nagata, Naoyoshi, Niikiura, Ryota, Iwata, Eri, Hamada, Mariko, Kawai, Yusuke, Fujimiya, Tatsuhiro, Takeuchi, Hironori, Unezaki, Sakae, Kawai, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8553963/
https://www.ncbi.nlm.nih.gov/pubmed/34721043
http://dx.doi.org/10.3389/fphar.2021.759249