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Cost-Effectiveness of Testing for NS5A Resistance to Optimize Treatment of Elbasvir/Grazoprevir for Chronic Hepatitis C in China

Objectives: Baseline presence of nonstructural protein 5A (NS5A) resistance-associated variants can attenuate the efficacy of new direct-acting antivirals. A potential method to attain the higher efficacy would be to screen for NS5A polymorphisms prior to the initiation of therapy and to adjust the...

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Detalles Bibliográficos
Autores principales: Liu, Jinyu, Zhang, Yu, Wu, Bin, Wang, Sen, Bin-Chia Wu, David, You, Ruxu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8554024/
https://www.ncbi.nlm.nih.gov/pubmed/34721016
http://dx.doi.org/10.3389/fphar.2021.717504