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Transcriptomic Analysis Identifies Complement Component 3 as a Potential Predictive Biomarker for Chemotherapy Resistance in Colorectal Cancer

Objective: 5-fluorouracil- and oxaliplatin-based FOLFOX regimens are mainstay chemotherapeutics for colorectal cancer (CRC) but drug resistance represents a major therapeutic challenge. To improve patient survival, there is a need to identify resistance genes to better understand the mechanisms unde...

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Detalles Bibliográficos
Autores principales: He, Xiao-Shun, Zou, Sheng-Yi, Yao, Jia-Lu, Yu, Wangjianfei, Deng, Zhi-Yong, Wang, Jing-Ru, Gan, Wen-Juan, Wan, Shan, Yang, Xiao-Qin, Wu, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8554154/
https://www.ncbi.nlm.nih.gov/pubmed/34722636
http://dx.doi.org/10.3389/fmolb.2021.763652