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Computational modeling of RNase, antisense ORF0 RNA, and intracellular compartmentation and their impact on the life cycle of the line retrotransposon

Nearly half of the human genome is occupied by repetitive sequences of ancient virus-like genetic elements. The largest class, comprising 17% of the genome, belong to the type 1 Long INterspersed Elements (LINE-1) and are the only class capable of autonomous propagation in the genome. When epigeneti...

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Detalles Bibliográficos
Autores principales: Martin, Michael David, Brown, David N., Ramos, Kenneth S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8554170/
https://www.ncbi.nlm.nih.gov/pubmed/34765087
http://dx.doi.org/10.1016/j.csbj.2021.10.003