Graded RhoA GTPase Expression in Treg Cells Distinguishes Tumor Immunity From Autoimmunity

RhoA of the Rho GTPase family is prenylated at its C-terminus. Prenylation of RhoA has been shown to control T helper 17 (Th17) cell-mediated colitis. By characterizing T cell-specific RhoA conditional knockout mice, we have recently shown that RhoA is required for Th2 and Th17 cell differentiation...

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Detalles Bibliográficos
Autores principales: Kalim, Khalid W., Yang, Jun-Qi, Modur, Vishnu, Nguyen, Phuong, Li, Yuan, Zheng, Yi, Guo, Fukun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8554290/
https://www.ncbi.nlm.nih.gov/pubmed/34721389
http://dx.doi.org/10.3389/fimmu.2021.726393

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8554290/
https://www.ncbi.nlm.nih.gov/pubmed/34721389
http://dx.doi.org/10.3389/fimmu.2021.726393

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