High ATP Production Fuels Cancer Drug Resistance and Metastasis: Implications for Mitochondrial ATP Depletion Therapy

Recently, we presented evidence that high mitochondrial ATP production is a new therapeutic target for cancer treatment. Using ATP as a biomarker, we isolated the “metabolically fittest” cancer cells from the total cell population. Importantly, ATP-high cancer cells were phenotypically the most aggr...

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Detalles Bibliográficos
Autores principales: Fiorillo, Marco, Ózsvári, Béla, Sotgia, Federica, Lisanti, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8554334/
https://www.ncbi.nlm.nih.gov/pubmed/34722292
http://dx.doi.org/10.3389/fonc.2021.740720

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8554334/
https://www.ncbi.nlm.nih.gov/pubmed/34722292
http://dx.doi.org/10.3389/fonc.2021.740720

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