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Acetyl-CoA carboxylase inhibitors in non-alcoholic steatohepatitis: Is there a benefit?
De novo lipogenesis (DNL) plays an important role in the pathogenesis of hepatic steatosis and also appears to be implicated in hepatic inflammation and fibrosis. Accordingly, the inhibition of acetyl-CoA carboxylase, which catalyzes the rate-limiting step of DNL, might represent a useful approach i...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Baishideng Publishing Group Inc
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8554398/ https://www.ncbi.nlm.nih.gov/pubmed/34754150 http://dx.doi.org/10.3748/wjg.v27.i39.6522 |