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Acetyl-CoA carboxylase inhibitors in non-alcoholic steatohepatitis: Is there a benefit?

De novo lipogenesis (DNL) plays an important role in the pathogenesis of hepatic steatosis and also appears to be implicated in hepatic inflammation and fibrosis. Accordingly, the inhibition of acetyl-CoA carboxylase, which catalyzes the rate-limiting step of DNL, might represent a useful approach i...

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Detalles Bibliográficos
Autores principales:	Neokosmidis, Georgios, Cholongitas, Evangelos, Tziomalos, Konstantinos
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Baishideng Publishing Group Inc 2021
Materias:	Frontier
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8554398/ https://www.ncbi.nlm.nih.gov/pubmed/34754150 http://dx.doi.org/10.3748/wjg.v27.i39.6522

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