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Type 2 diabetes sex-specific effects associated with E167K coding variant in TM6SF2

The rs58542926C >T (E167K) variant of the transmembrane 6 superfamily member 2 gene (TM6SF2) is associated with increased risks for nonalcoholic fatty liver disease (NAFLD) and type 2 diabetes (T2D). Nevertheless, the role of the TM6SF2 rs58542926 variant in glucose metabolism is poorly understoo...

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Detalles Bibliográficos
Autores principales: Fan, Yanbo, Wolford, Brooke N., Lu, Haocheng, Liang, Wenying, Sun, Jinjian, Zhou, Wei, Rom, Oren, Mahajan, Anubha, Surakka, Ida, Graham, Sarah E., Liu, Zhipeng, Kim, Hyunbae, Ramdas, Shweta, Fritsche, Lars G., Nielsen, Jonas B., Gabrielsen, Maiken Elvestad, Hveem, Kristian, Yang, Dongshan, Song, Jun, Garcia-Barrio, Minerva T., Zhang, Jifeng, Liu, Wanqing, Zhang, Kezhong, Willer, Cristen J., Chen, Y. Eugene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8554487/
https://www.ncbi.nlm.nih.gov/pubmed/34746691
http://dx.doi.org/10.1016/j.isci.2021.103196