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The eIF2 kinase GCN2 directs keratinocyte collective cell migration during wound healing via coordination of reactive oxygen species and amino acids

Healing of cutaneous wounds requires the collective migration of epithelial keratinocytes to seal the wound bed from the environment. However, the signaling events that coordinate this collective migration are unclear. In this report, we address the role of phosphorylation of eukaryotic initiation f...

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Detalles Bibliográficos
Autores principales: Miles, Rebecca R., Amin, Parth H., Diaz, Miguel Barriera, Misra, Jagannath, Aukerman, Erica, Das, Amitava, Ghosh, Nandini, Guith, Tanner, Knierman, Michael D., Roy, Sashwati, Spandau, Dan F, Wek, Ronald C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8554533/
https://www.ncbi.nlm.nih.gov/pubmed/34597669
http://dx.doi.org/10.1016/j.jbc.2021.101257