Histone lysine demethylase 4B regulates general and unique gene expression signatures in hypoxic cancer cells

The hypoxic tumor microenvironment promotes tumor survival by inducing the expression of genes involved in angiogenesis and metastasis. As a direct target of hypoxia‐inducible factor, lysine demethylase 4B (KDM4B) is overexpressed in multiple cancers, suggesting that a general KDM4B regulatory mecha...

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Detalles Bibliográficos
Autores principales: Qiu, Lei, Meng, Yang, Wang, Lingli, Gunewardena, Sumedha, Liu, Sicheng, Han, Junhong, Krieg, Adam J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8554665/
https://www.ncbi.nlm.nih.gov/pubmed/34766154
http://dx.doi.org/10.1002/mco2.85

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8554665/
https://www.ncbi.nlm.nih.gov/pubmed/34766154
http://dx.doi.org/10.1002/mco2.85

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