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Histone lysine demethylase 4B regulates general and unique gene expression signatures in hypoxic cancer cells
The hypoxic tumor microenvironment promotes tumor survival by inducing the expression of genes involved in angiogenesis and metastasis. As a direct target of hypoxia‐inducible factor, lysine demethylase 4B (KDM4B) is overexpressed in multiple cancers, suggesting that a general KDM4B regulatory mecha...
Autores principales: | Qiu, Lei, Meng, Yang, Wang, Lingli, Gunewardena, Sumedha, Liu, Sicheng, Han, Junhong, Krieg, Adam J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8554665/ https://www.ncbi.nlm.nih.gov/pubmed/34766154 http://dx.doi.org/10.1002/mco2.85 |
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