A Novel Homozygous Missense Mutation in the Zinc Finger DNA Binding Domain of GLI1 Causes Recessive Post-Axial Polydactyly

Background: Polydactyly is a prevalent digit abnormality characterized by having extra digits/toes. Mutations in eleven known genes have been associated to cause nonsyndromic polydactyly: GLI3, GLI1, ZRS regulating LMBR1, IQCE, ZNF141, PITX1, MIPOL1, FAM92A, STKLD1, KIAA0825, and DACH1. Method: A si...

Descripción completa

Detalles Bibliográficos
Autores principales: Umair, Muhammad, Ahmad, Farooq, Ahmad, Saeed, Alam, Qamre, Rehan, Mohd, Alqosaibi, Amany I., Alnamshan, Mashael M., Rafeeq, Misbahuddin M, Haque, Shahnaz, Sain, Ziaullah M, Ismail, Muhammad, Alfadhel, Majid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8554680/
https://www.ncbi.nlm.nih.gov/pubmed/34721536
http://dx.doi.org/10.3389/fgene.2021.746949

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8554680/
https://www.ncbi.nlm.nih.gov/pubmed/34721536
http://dx.doi.org/10.3389/fgene.2021.746949

Ejemplares similares