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Integration of SARS-CoV-2 RNA in infected human cells by retrotransposons: an unlikely hypothesis and old viral relationships

Zhang et al. (Proc Natl Acad Sci 118:e2105968118, 2021) recently reported that SARS-CoV-2 RNA can be retrotranscribed and integrated into the DNA of human cells by the L1 retrotransposon machinery. This phenomenon could cause persistence of viral sequences in patients and may explain the prolonged P...

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Detalles Bibliográficos
Autores principales: Grandi, Nicole, Tramontano, Enzo, Berkhout, Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8554740/
https://www.ncbi.nlm.nih.gov/pubmed/34715873
http://dx.doi.org/10.1186/s12977-021-00578-w