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Snake venom phospholipase A(2)s exhibit strong virucidal activity against SARS-CoV-2 and inhibit the viral spike glycoprotein interaction with ACE2

The COVID-19 pandemic caused by SARS-CoV-2 requires new treatments both to alleviate the symptoms and to prevent the spread of this disease. Previous studies demonstrated good antiviral and virucidal activity of phospholipase A(2)s (PLA(2)s) from snake venoms against viruses from different families...

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Detalles Bibliográficos
Autores principales: Siniavin, Andrei E., Streltsova, Maria A., Nikiforova, Maria A., Kudryavtsev, Denis S., Grinkina, Svetlana D., Gushchin, Vladimir A., Mozhaeva, Vera A., Starkov, Vladislav G., Osipov, Alexey V., Lummis, Sarah C. R., Tsetlin, Victor I., Utkin, Yuri N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8554752/
https://www.ncbi.nlm.nih.gov/pubmed/34714362
http://dx.doi.org/10.1007/s00018-021-03985-6