Determining Sequence-Dependent DNA Oligonucleotide Hybridization and Dehybridization Mechanisms Using Coarse-Grained Molecular Simulation, Markov State Models, and Infrared Spectroscopy

[Image: see text] A robust understanding of the sequence-dependent thermodynamics of DNA hybridization has enabled rapid advances in DNA nanotechnology. A fundamental understanding of the sequence-dependent kinetics and mechanisms of hybridization and dehybridization remains comparatively underdevel...

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Detalles Bibliográficos
Autores principales: Jones, Michael S., Ashwood, Brennan, Tokmakoff, Andrei, Ferguson, Andrew L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8554761/
https://www.ncbi.nlm.nih.gov/pubmed/34644072
http://dx.doi.org/10.1021/jacs.1c05219

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8554761/
https://www.ncbi.nlm.nih.gov/pubmed/34644072
http://dx.doi.org/10.1021/jacs.1c05219

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