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Determining Sequence-Dependent DNA Oligonucleotide Hybridization and Dehybridization Mechanisms Using Coarse-Grained Molecular Simulation, Markov State Models, and Infrared Spectroscopy

[Image: see text] A robust understanding of the sequence-dependent thermodynamics of DNA hybridization has enabled rapid advances in DNA nanotechnology. A fundamental understanding of the sequence-dependent kinetics and mechanisms of hybridization and dehybridization remains comparatively underdevel...

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Detalles Bibliográficos
Autores principales:	Jones, Michael S., Ashwood, Brennan, Tokmakoff, Andrei, Ferguson, Andrew L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2021
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8554761/ https://www.ncbi.nlm.nih.gov/pubmed/34644072 http://dx.doi.org/10.1021/jacs.1c05219

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