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Inflammation‐induced left ventricular fibrosis is partially mediated by tumor necrosis factor‐α

OBJECTIVE: To determine the mechanisms of inflammation‐induced left ventricular (LV) remodeling and effects of blocking circulating tumor necrosis factor alpha (TNF‐α) in a model of systemic inflammation. METHODS: Seventy Sprague‐Dawley rats were divided into three groups: the control group, the col...

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Detalles Bibliográficos
Autores principales: Manilall, Ashmeetha, Mokotedi, Lebogang, Gunter, Sulè, Le Roux, Regina, Fourie, Serena, Flanagan, Colleen A., Millen, Aletta M.E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8554769/
https://www.ncbi.nlm.nih.gov/pubmed/34713972
http://dx.doi.org/10.14814/phy2.15062