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Optimized Loopable Translation as a Platform for the Synthesis of Repetitive Proteins
[Image: see text] The expression of long proteins with repetitive amino acid sequences often presents a challenge in recombinant systems. To overcome this obstacle, we report a genetic construct that circularizes mRNA in vivo by rearranging the topology of a group I self-splicing intron from T4 bact...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8554844/ https://www.ncbi.nlm.nih.gov/pubmed/34729417 http://dx.doi.org/10.1021/acscentsci.1c00574 |