Allergens of the urushiol family promote mitochondrial dysfunction by inhibiting the electron transport at the level of cytochromes b and chemically modify cytochrome c(1)

BACKGROUND: Urushiols are pro-electrophilic haptens that cause severe contact dermatitis mediated by CD8(+) effector T-cells and downregulated by CD4(+) T-cells. However, the molecular mechanism by which urushiols stimulate innate immunity in the initial stages of this allergic reaction is poorly un...

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Detalles Bibliográficos
Autores principales: Pacheco, Rodrigo, Quezada, Sergio A., Kalergis, Alexis M., Becker, María Inés, Ferreira, Jorge, De Ioannes, Alfredo E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8554850/
https://www.ncbi.nlm.nih.gov/pubmed/34711292
http://dx.doi.org/10.1186/s40659-021-00357-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8554850/
https://www.ncbi.nlm.nih.gov/pubmed/34711292
http://dx.doi.org/10.1186/s40659-021-00357-z

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