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Perturbation of PI3K/Akt signaling affected autophagy modulation in dystrophin-deficient myoblasts
BACKGROUND: The absence of dystrophin has gave a massive impact on myotube development in Muscular Dystrophy pathogenesis. One of the conserved signaling pathways involved in skeletal muscle differentiation is the PI3K/Akt/mTOR pathway that plays a vital role in autophagy regulation. To further unde...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8554905/ https://www.ncbi.nlm.nih.gov/pubmed/34706731 http://dx.doi.org/10.1186/s12964-021-00785-0 |