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Perturbation of PI3K/Akt signaling affected autophagy modulation in dystrophin-deficient myoblasts

BACKGROUND: The absence of dystrophin has gave a massive impact on myotube development in Muscular Dystrophy pathogenesis. One of the conserved signaling pathways involved in skeletal muscle differentiation is the PI3K/Akt/mTOR pathway that plays a vital role in autophagy regulation. To further unde...

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Detalles Bibliográficos
Autores principales:	Yazid, Muhammad Dain, Hung-Chih, Chen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8554905/ https://www.ncbi.nlm.nih.gov/pubmed/34706731 http://dx.doi.org/10.1186/s12964-021-00785-0

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