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Long noncoding RNA SGO1-AS1 inactivates TGFβ signaling by facilitating TGFB1/2 mRNA decay and inhibits gastric carcinoma metastasis

BACKGROUND: Although thousands of long noncoding RNAs (lncRNAs) have been annotated, only a few lncRNAs have been characterized functionally. In this study, we aimed to identify novel lncRNAs involved in the progression of gastric carcinoma (GC) and explore their regulatory mechanisms and clinical s...

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Detalles Bibliográficos
Autores principales: Huang, Donglan, Zhang, Ke, Zheng, Wenying, Zhang, Ruixin, Chen, Jiale, Du, Nan, Xia, Yuanyuan, Long, Yan, Gu, Yixue, Xu, Jianhua, Deng, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8555099/
https://www.ncbi.nlm.nih.gov/pubmed/34706749
http://dx.doi.org/10.1186/s13046-021-02140-0