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Centrality of drug targets in protein networks
BACKGROUND: In the pharmaceutical industry, competing for few validated drug targets there is a drive to identify new ways of therapeutic intervention. Here, we attempted to define guidelines to evaluate a target’s ‘fitness’ based on its node characteristics within annotated protein functional netwo...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8555226/ https://www.ncbi.nlm.nih.gov/pubmed/34715787 http://dx.doi.org/10.1186/s12859-021-04342-x |