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Centrality of drug targets in protein networks

BACKGROUND: In the pharmaceutical industry, competing for few validated drug targets there is a drive to identify new ways of therapeutic intervention. Here, we attempted to define guidelines to evaluate a target’s ‘fitness’ based on its node characteristics within annotated protein functional netwo...

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Detalles Bibliográficos
Autor principal: Viacava Follis, Ariele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8555226/
https://www.ncbi.nlm.nih.gov/pubmed/34715787
http://dx.doi.org/10.1186/s12859-021-04342-x

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