Immunoprofiling of early, untreated rheumatoid arthritis using mass cytometry reveals an activated basophil subset inversely linked to ACPA status

BACKGROUND: Autoantibody production is a hallmark of rheumatoid arthritis (RA). Anti-citrullinated protein antibodies (ACPA) are highly disease-specific, and their presence is associated with more severe disease and poor prognosis compared to ACPA-negative patients. However, the immune cell composit...

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Detalles Bibliográficos
Autores principales: Koppejan, H., Hameetman, M., Beyrend, G., van Unen, V., Kwekkeboom, J. C., van der Helm-van Mil, A. H., Toes, R. E. M., van Gaalen, F. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8555233/
https://www.ncbi.nlm.nih.gov/pubmed/34715910
http://dx.doi.org/10.1186/s13075-021-02630-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8555233/
https://www.ncbi.nlm.nih.gov/pubmed/34715910
http://dx.doi.org/10.1186/s13075-021-02630-8

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