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Immunoprofiling of early, untreated rheumatoid arthritis using mass cytometry reveals an activated basophil subset inversely linked to ACPA status

BACKGROUND: Autoantibody production is a hallmark of rheumatoid arthritis (RA). Anti-citrullinated protein antibodies (ACPA) are highly disease-specific, and their presence is associated with more severe disease and poor prognosis compared to ACPA-negative patients. However, the immune cell composit...

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Detalles Bibliográficos
Autores principales:	Koppejan, H., Hameetman, M., Beyrend, G., van Unen, V., Kwekkeboom, J. C., van der Helm-van Mil, A. H., Toes, R. E. M., van Gaalen, F. A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8555233/ https://www.ncbi.nlm.nih.gov/pubmed/34715910 http://dx.doi.org/10.1186/s13075-021-02630-8

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