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The rates of stem cell division determine the cell cycle lengths of its lineage

Adult stem cells and their transit-amplifying progeny alter their proliferation rates to maintain tissue homeostasis. To test how the division rates of stem cells and transit-amplifying progeny affect tissue growth and differentiation, we developed a computation strategy that estimates the average c...

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Detalles Bibliográficos
Autores principales: Gadre, Purna, Nitsure, Nitin, Mazumdar, Debasmita, Gupta, Samir, Ray, Krishanu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8555441/
https://www.ncbi.nlm.nih.gov/pubmed/34746698
http://dx.doi.org/10.1016/j.isci.2021.103232