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Rare type I CBFβ/MYH11 fusion transcript in primary acute myeloid leukemia with inv(16)(p13.1q22): a case report

Inv(16)(p13.1q22) in acute myeloid leukemia (AML) is a common chromosomal abnormality. It leads to the core-binding factor ß-subunit (CBFβ)/smooth muscle myosin heavy chain 11 (MYH11) fusion gene. Different breakpoints were observed in the CBFβ gene at 16q22 and the MYH11 gene at 16p13.1. For this r...

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Detalles Bibliográficos
Autores principales: Zhang, Wenyi, Wang, Hainan, Zhang, Peilei, Li, Hongliang, Ma, Xiaoli, Liu, Hongxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8555453/
https://www.ncbi.nlm.nih.gov/pubmed/34730684
http://dx.doi.org/10.1590/1414-431X2021e11605