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Differential Impact of Severity and Duration of Status Epilepticus, Medical Countermeasures, and a Disease-Modifier, Saracatinib, on Brain Regions in the Rat Diisopropylfluorophosphate Model

Acute organophosphate (OP) toxicity poses a significant threat to both military and civilian personnel as it can lead to a variety of cholinergic symptoms including the development of status epilepticus (SE). Depending on its severity, SE can lead to a spectrum of neurological changes including neur...

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Detalles Bibliográficos
Autores principales: Gage, Meghan, Putra, Marson, Gomez-Estrada, Crystal, Golden, Madison, Wachter, Logan, Gard, Megan, Thippeswamy, Thimmasettappa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8555467/
https://www.ncbi.nlm.nih.gov/pubmed/34720886
http://dx.doi.org/10.3389/fncel.2021.772868