Cargando…
Differential Impact of Severity and Duration of Status Epilepticus, Medical Countermeasures, and a Disease-Modifier, Saracatinib, on Brain Regions in the Rat Diisopropylfluorophosphate Model
Acute organophosphate (OP) toxicity poses a significant threat to both military and civilian personnel as it can lead to a variety of cholinergic symptoms including the development of status epilepticus (SE). Depending on its severity, SE can lead to a spectrum of neurological changes including neur...
Autores principales: | Gage, Meghan, Putra, Marson, Gomez-Estrada, Crystal, Golden, Madison, Wachter, Logan, Gard, Megan, Thippeswamy, Thimmasettappa |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8555467/ https://www.ncbi.nlm.nih.gov/pubmed/34720886 http://dx.doi.org/10.3389/fncel.2021.772868 |
Ejemplares similares
-
Saracatinib, a Src Tyrosine Kinase Inhibitor, as a Disease Modifier in the Rat DFP Model: Sex Differences, Neurobehavior, Gliosis, Neurodegeneration, and Nitro-Oxidative Stress
por: Gage, Meghan, et al.
Publicado: (2021) -
Gut dysbiosis following organophosphate, diisopropylfluorophosphate (DFP), intoxication and saracatinib oral administration
por: Gage, Meghan, et al.
Publicado: (2022) -
Characterization of Cortical Glial Scars in the Diisopropylfluorophosphate (DFP) Rat Model of Epilepsy
por: Gage, Meghan, et al.
Publicado: (2022) -
Peripheral and central effects of NADPH oxidase inhibitor, mitoapocynin, in a rat model of diisopropylfluorophosphate (DFP) toxicity
por: Meyer, Christina, et al.
Publicado: (2023) -
DFP-Induced Status Epilepticus Severity in Mixed-Sex Cohorts of Adult Rats Housed in the Same Room: Behavioral and EEG Comparisons
por: Rao, Nikhil S., et al.
Publicado: (2022)