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Alterations of DNA methylation during adipogenesis differentiation of mesenchymal stem cells isolated from adipose tissue of patients with obesity is associated with type 2 diabetes

Adipogenesis regulation is crucial for mature adipocyte function. In obesity, a major driver of type 2 diabetes (T2D), this process is disrupted and remains poorly characterized. Here we identified altered DNA methylation profiles in diabetic obese patients, during three adipocytes differentiation s...

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Detalles Bibliográficos
Autores principales: Mirzaeicheshmeh, Elaheh, Zerrweck, Carlos, Centeno-Cruz, Federico, Baca-Peynado, Paulina, Martinez-Hernandez, Angélica, García-Ortiz, Humberto, Contreras-Cubas, Cecilia, Salas-Martínez, María Guadalupe, Saldaña-Alvarez, Yolanda, Mendoza-Caamal, Elvia C., Barajas-Olmos, Francisco, Orozco, Lorena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8555535/
https://www.ncbi.nlm.nih.gov/pubmed/34699309
http://dx.doi.org/10.1080/21623945.2021.1978157