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Interplay between splicing and transcriptional pausing exerts genome-wide control over alternative polyadenylation

Recent studies have identified multiple polyadenylation sites in nearly all mammalian genes. Although these are interpreted as evidence for alternative polyadenylation, our knowledge of the underlying mechanisms is still limited. Most studies only consider the immediate surroundings of gene ends, ev...

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Detalles Bibliográficos
Autores principales: Mora Gallardo, Carmen, Sánchez de Diego, Ainhoa, Martínez-A, Carlos, van Wely, Karel H.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8555548/
https://www.ncbi.nlm.nih.gov/pubmed/34365909
http://dx.doi.org/10.1080/21541264.2021.1959244