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Nitrous oxide as an adjunctive therapy in major depressive disorder: a randomized controlled double-blind pilot trial
OBJECTIVE: Major depressive disorder (MDD) is related to glutamatergic dysfunction. Antagonists of glutamatergic N-methyl-D-aspartate receptor (NMDAR), such as ketamine, have antidepressant properties. Nitrous oxide (N(2)O) is also a NMDAR antagonist. Thus, this study aimed to evaluate the effects o...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Associação Brasileira de Psiquiatria
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8555644/ https://www.ncbi.nlm.nih.gov/pubmed/33605397 http://dx.doi.org/10.1590/1516-4446-2020-1543 |