Paradoxical Potentiation of Acid-Sensing Ion Channel 3 (ASIC3) by Amiloride via Multiple Mechanisms and Sites Within the Channel

Acid-Sensing Ion Channels (ASICs) are proton-gated sodium-selective cation channels that have emerged as metabolic and pain sensors in peripheral sensory neurons and contribute to neurotransmission in the CNS. These channels and their related degenerin/epithelial sodium channel (DEG/ENaC) family are...

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Detalles Bibliográficos
Autores principales: Matasic, Daniel S., Holland, Nicholas, Gautam, Mamta, Gibbons, David D., Kusama, Nobuyoshi, Harding, Anne M. S., Shah, Viral S., Snyder, Peter M., Benson, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8555766/
https://www.ncbi.nlm.nih.gov/pubmed/34721074
http://dx.doi.org/10.3389/fphys.2021.750696

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8555766/
https://www.ncbi.nlm.nih.gov/pubmed/34721074
http://dx.doi.org/10.3389/fphys.2021.750696

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