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Paradoxical Potentiation of Acid-Sensing Ion Channel 3 (ASIC3) by Amiloride via Multiple Mechanisms and Sites Within the Channel

Acid-Sensing Ion Channels (ASICs) are proton-gated sodium-selective cation channels that have emerged as metabolic and pain sensors in peripheral sensory neurons and contribute to neurotransmission in the CNS. These channels and their related degenerin/epithelial sodium channel (DEG/ENaC) family are...

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Detalles Bibliográficos
Autores principales:	Matasic, Daniel S., Holland, Nicholas, Gautam, Mamta, Gibbons, David D., Kusama, Nobuyoshi, Harding, Anne M. S., Shah, Viral S., Snyder, Peter M., Benson, Christopher J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8555766/ https://www.ncbi.nlm.nih.gov/pubmed/34721074 http://dx.doi.org/10.3389/fphys.2021.750696

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