Cargando…

ERBB3-dependent AKT and ERK pathways are essential for atrioventricular cushion development in mouse embryos

ERBB family members and their ligands play an essential role in embryonic heart development and adult heart physiology. Among them, ERBB3 is a binding partner of ERBB2; the ERBB2/3 complex mediates downstream signaling for cell proliferation. ERBB3 has seven consensus binding sites to the p85 regula...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Kyoungmi, Lee, Daekee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8555822/
https://www.ncbi.nlm.nih.gov/pubmed/34714866
http://dx.doi.org/10.1371/journal.pone.0259426