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Cross-species screening platforms identify EPS-8 as a critical link for mitochondrial stress and actin stabilization

The dysfunction of mitochondria is associated with the physiological consequences of aging and many age-related diseases. Therefore, critical quality control mechanisms exist to protect mitochondrial functions, including the unfolded protein response of the mitochondria (UPR(MT)). However, it is sti...

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Detalles Bibliográficos
Autores principales: Moehle, Erica A., Higuchi-Sanabria, Ryo, Tsui, C. Kimberly, Homentcovschi, Stefan, Tharp, Kevin M., Zhang, Hanlin, Chi, Hannah, Joe, Larry, de los Rios Rogers, Mattias, Sahay, Arushi, Kelet, Naame, Benitez, Camila, Bar-Ziv, Raz, Garcia, Gilberto, Shen, Koning, Frankino, Phillip A., Schinzel, Robert T., Shalem, Ophir, Dillin, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8555897/
https://www.ncbi.nlm.nih.gov/pubmed/34714674
http://dx.doi.org/10.1126/sciadv.abj6818