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The mechanosensitive Piezo1 channel controls endosome trafficking for an efficient cytokinetic abscission

Mechanical forces are exerted throughout cytokinesis, the final step of cell division. Yet, how forces are transduced and affect the signaling dynamics of cytokinetic proteins remains poorly characterized. We now show that the mechanosensitive Piezo1 channel is activated at the intercellular bridge...

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Detalles Bibliográficos
Autores principales: Carrillo-Garcia, Julia, Herrera-Fernández, Víctor, Serra, Selma A., Rubio-Moscardo, Fanny, Vogel-Gonzalez, Marina, Doñate-Macian, Pablo, Hevia, Covadonga F., Pujades, Cristina, Valverde, Miguel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8555900/
https://www.ncbi.nlm.nih.gov/pubmed/34714681
http://dx.doi.org/10.1126/sciadv.abi7785