A unified framework identifies novel links between plasma lipids and diseases from electronic medical records across large-scale cohorts

Plasma lipids are known heritable risk factors for cardiovascular disease, but increasing evidence also supports shared genetics with diseases of other organ systems. We devised a comprehensive three-phase framework to identify novel lipid-associated genes and study the relationships between lipids,...

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Detalles Bibliográficos
Autores principales: Veturi, Yogasudha, Lucas, Anastasia, Bradford, Yuki, Hui, Daniel, Dudek, Scott, Theusch, Elizabeth, Verma, Anurag, Miller, Jason E., Kullo, Iftikhar, Hakonarson, Hakon, Sleiman, Patrick, Schaid, Daniel, Stein, Charles M., Edwards, Digna R. Velez, Feng, QiPing, Wei, Wei-Qi, Medina, Marisa W., Krauss, Ronald, Hoffmann, Thomas J., Risch, Neil, Voight, Benjamin F., Rader, Daniel J., Ritchie, Marylyn D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8555954/
https://www.ncbi.nlm.nih.gov/pubmed/34140684
http://dx.doi.org/10.1038/s41588-021-00879-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8555954/
https://www.ncbi.nlm.nih.gov/pubmed/34140684
http://dx.doi.org/10.1038/s41588-021-00879-y

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