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Mechanical overstimulation causes acute injury and synapse loss followed by fast recovery in lateral-line neuromasts of larval zebrafish

Excess noise damages sensory hair cells, resulting in loss of synaptic connections with auditory nerves and, in some cases, hair-cell death. The cellular mechanisms underlying mechanically induced hair-cell damage and subsequent repair are not completely understood. Hair cells in neuromasts of larva...

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Detalles Bibliográficos
Autores principales: Holmgren, Melanie, Ravicz, Michael E, Hancock, Kenneth E, Strelkova, Olga, Kallogjeri, Dorina, Indzhykulian, Artur A, Warchol, Mark E, Sheets, Lavinia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8555980/
https://www.ncbi.nlm.nih.gov/pubmed/34665127
http://dx.doi.org/10.7554/eLife.69264