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Tbx5 drives Aldh1a2 expression to regulate a RA-Hedgehog-Wnt gene regulatory network coordinating cardiopulmonary development

The gene regulatory networks that coordinate the development of the cardiac and pulmonary systems are essential for terrestrial life but poorly understood. The T-box transcription factor Tbx5 is critical for both pulmonary specification and heart development, but how these activities are mechanistic...

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Detalles Bibliográficos
Autores principales: Rankin, Scott A, Steimle, Jeffrey D, Yang, Xinan H, Rydeen, Ariel B, Agarwal, Kunal, Chaturvedi, Praneet, Ikegami, Kohta, Herriges, Michael J, Moskowitz, Ivan P, Zorn, Aaron M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8555986/
https://www.ncbi.nlm.nih.gov/pubmed/34643182
http://dx.doi.org/10.7554/eLife.69288