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β-Catenin-NF-κB-CFTR interactions in cholangiocytes regulate inflammation and fibrosis during ductular reaction

Expansion of biliary epithelial cells (BECs) during ductular reaction (DR) is observed in liver diseases including cystic fibrosis (CF), and associated with inflammation and fibrosis, albeit without complete understanding of underlying mechanism. Using two different genetic mouse knockouts of β-cate...

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Detalles Bibliográficos
Autores principales: Hu, Shikai, Russell, Jacquelyn O, Liu, Silvia, Cao, Catherine, McGaughey, Jackson, Rai, Ravi, Kosar, Karis, Tao, Junyan, Hurley, Edward, Poddar, Minakshi, Singh, Sucha, Bell, Aaron, Shin, Donghun, Raeman, Reben, Singhi, Aatur D, Nejak-Bowen, Kari, Ko, Sungjin, Monga, Satdarshan P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8555990/
https://www.ncbi.nlm.nih.gov/pubmed/34609282
http://dx.doi.org/10.7554/eLife.71310