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β-Catenin-NF-κB-CFTR interactions in cholangiocytes regulate inflammation and fibrosis during ductular reaction
Expansion of biliary epithelial cells (BECs) during ductular reaction (DR) is observed in liver diseases including cystic fibrosis (CF), and associated with inflammation and fibrosis, albeit without complete understanding of underlying mechanism. Using two different genetic mouse knockouts of β-cate...
Autores principales: | Hu, Shikai, Russell, Jacquelyn O, Liu, Silvia, Cao, Catherine, McGaughey, Jackson, Rai, Ravi, Kosar, Karis, Tao, Junyan, Hurley, Edward, Poddar, Minakshi, Singh, Sucha, Bell, Aaron, Shin, Donghun, Raeman, Reben, Singhi, Aatur D, Nejak-Bowen, Kari, Ko, Sungjin, Monga, Satdarshan P |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8555990/ https://www.ncbi.nlm.nih.gov/pubmed/34609282 http://dx.doi.org/10.7554/eLife.71310 |
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