Parecoxib mitigates lung ischemia-reperfusion injury in rats by reducing oxidative stress and inflammation and up-regulating HO-1 expression

PURPOSE: To investigate the protective effect of parecoxib against lung ischemia-reperfusion injury (LIRI) in rats and the mechanism. METHODS: Thirty rats were divided into sham-operated, LIRI and LIRI+parecoxib groups. LIRI model (ischemia for 60 min, followed by reperfusion for 120 min) was constr...

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Detalles Bibliográficos
Autores principales: Qin, Jun, Su, Xunling, Jin, Xin, Zhao, Jiayi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8555996/
https://www.ncbi.nlm.nih.gov/pubmed/34705944
http://dx.doi.org/10.1590/ACB360901

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8555996/
https://www.ncbi.nlm.nih.gov/pubmed/34705944
http://dx.doi.org/10.1590/ACB360901

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