SPP1 Promotes Enzalutamide Resistance and Epithelial-Mesenchymal-Transition Activation in Castration-Resistant Prostate Cancer via PI3K/AKT and ERK1/2 Pathways

The bottleneck arising from castration-resistant prostate cancer (CRPC) treatment is its high metastasis potential and antiandrogen drug resistance, which severely affects survival time of prostate cancer (PCa) patients. Secreted phosphoprotein 1 (SPP1) is a cardinal mediator of tumor-associated inf...

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Detalles Bibliográficos
Autores principales: Pang, Xiaocong, Zhang, Junling, He, Xu, Gu, Yanlun, Qian, Bin-zhi, Xie, Ran, Yu, Wei, Zhang, Xiaodan, Li, Teng, Shi, Xuedong, Zhou, Ying, Cui, Yimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8556132/
https://www.ncbi.nlm.nih.gov/pubmed/34721759
http://dx.doi.org/10.1155/2021/5806602

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