A missense mutation in Pitx2 leads to early-onset glaucoma via NRF2-YAP1 axis

Glaucoma is a leading cause of blindness, affecting 70 million people worldwide. Owing to the similarity in anatomy and physiology between human and mouse eyes and the ability to genetically manipulate mice, mouse models are an invaluable resource for studying mechanisms underlying disease phenotype...

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Detalles Bibliográficos
Autores principales: Yang, Yeming, Li, Xiao, Wang, Jieping, Tan, Junkai, Fitzmaurice, Bernie, Nishina, Patsy M., Sun, Kuanxiang, Tian, Wanli, Liu, Wenjing, Liu, Xuyang, Chang, Bo, Zhu, Xianjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8556256/
https://www.ncbi.nlm.nih.gov/pubmed/34716303
http://dx.doi.org/10.1038/s41419-021-04331-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8556256/
https://www.ncbi.nlm.nih.gov/pubmed/34716303
http://dx.doi.org/10.1038/s41419-021-04331-1

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