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An intrinsically disordered nascent protein interacts with specific regions of the ribosomal surface near the exit tunnel

The influence of the ribosome on nascent chains is poorly understood, especially in the case of proteins devoid of signal or arrest sequences. Here, we provide explicit evidence for the interaction of specific ribosomal proteins with ribosome-bound nascent chains (RNCs). We target RNCs pertaining to...

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Detalles Bibliográficos
Autores principales: Guzman-Luna, Valeria, Fuchs, Andrew M., Allen, Anna J., Staikos, Alexios, Cavagnero, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8556260/
https://www.ncbi.nlm.nih.gov/pubmed/34716402
http://dx.doi.org/10.1038/s42003-021-02752-4