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Resolvin-D2 targets myogenic cells and improves muscle regeneration in Duchenne muscular dystrophy

Lack of dystrophin causes muscle degeneration, which is exacerbated by chronic inflammation and reduced regenerative capacity of muscle stem cells in Duchenne Muscular Dystrophy (DMD). To date, glucocorticoids remain the gold standard for the treatment of DMD. These drugs are able to slow down the p...

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Detalles Bibliográficos
Autores principales: Dort, Junio, Orfi, Zakaria, Fabre, Paul, Molina, Thomas, Conte, Talita C., Greffard, Karine, Pellerito, Ornella, Bilodeau, Jean-François, Dumont, Nicolas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8556273/
https://www.ncbi.nlm.nih.gov/pubmed/34716330
http://dx.doi.org/10.1038/s41467-021-26516-0